Fantasy Football Start 'Em Sit 'Em: Week 5 lineup advice, best matchups, DFS picks

The Week 5 fantasy start 'em, sit 'em decisions aren't getting any easier, are they? Heading into Week 5, backups QBs Trey Lance and Drew Lock seem poised to start, while handcuff RBs Damien Williams and Samaje Perine might suddenly be thrust into high-volume roles. Whenever there's a QB change, the ripple effects are felt throughout the entire team, making many question their WRs and TEs and seek lineup advice. As always, SN's Vinnie Iyer, aka "The Decider," is here to help those in season-long leagues and those looking for DFS tips.

It's important to remember that we have an early-morning Sunday kickoff this week, as the Jets and Falcons are set to do battle in London. Don't get caught off guard and leave any key Falcons and Jets on your bench (or in your lineup) by accident. 

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